Personalized Cancer Genomics: The Road Map to Clinical Implementation
نویسندگان
چکیده
منابع مشابه
Personalized cancer genomics: the road map to clinical implementation.
The promise of personalized medicine has been around for many years, and growth in the field is rapidly gaining momentum. The concept is to use information from an individual’s genomic, transcriptomic, and proteomic profiles to tailor a custom management plan for his or her disease based on an assessment of the disease’s risks and aggressiveness (1 ). A recent revolution in personalized medicin...
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Voltaire, after suffering an attack of smallpox, wrote in a letter to Baron de Breteuil, ‘‘.the diseases that afflict us are as different as the features on our faces’’ (1723). Systematic sequencing of cancer genomes in the last 5 years has unmasked the countless faces of cancer, laying bare the uniqueness of each patient’s tumor; in its cancer genes, its mutational processes, its clonal archit...
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personalized medicine is significantly changing the fundamentals of healthcare. genetic diagnostic tests are used in various parts of medicine – from initial screening to the diagnosis and finally treatment. investigations in fields of drug development indicate that oncology may lead other therapeutic areas in the number of targeted therapies on the marketplace as well as in the pipeline, expec...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2012
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2011.181073